Antitoxin and toxoid products for tetanus prevention
This page catalogs 2 standalone tetanus products: the historical equine antitoxin that provided passive protection beginning in the 1890s, and the tetanus toxoid licensed in 1938. Standalone tetanus vaccination is no longer administered in routine practice; all current tetanus immunization in the United States is delivered through combination products (DT, Td, DTP, DTaP, Tdap) cataloged on the Combination Vaccines page.
Last updated: April 2026.
| Trade Name | Generic Designation | Manufacturer | Vaccine Type | Regulatory Status & Year | Key Notes |
|---|---|---|---|---|---|
| Tetanus antitoxin (equine) | Horse-derived anti-tetanus serum | Various | Antitoxin (passive) | Historical (1890s) | Passive protection; still used in some settings |
| Tetanus toxoid | Formaldehyde-inactivated tetanus toxin | Various | Toxoid | FDA Licensed, 1938 | Always in combination today (DT, Td, DTP, DTaP, Tdap) |
Regulatory data sourced from FDA CBER Vaccines Licensed for Use in the United States (March 2026). Historical context informed by Khan, Shaz, The Ultimate Vaccine Timeline.