Diphtheria Vaccines
Antitoxins and toxoids (standalone)
This page catalogs 3 standalone diphtheria products — the historical antitoxin and individual toxoid formulations. Today, diphtheria toxoid is almost exclusively administered in combination vaccines.
Note: Diphtheria antigens appear in numerous combination vaccines. See the Combination Vaccines catalog for DTaP, Tdap, DT, Td, and hexavalent products.
Last updated: April 2026.
Diphtheria Product Catalog
| Trade Name | Generic Designation | Manufacturer | Vaccine Type | Regulatory Status & Year | Key Notes |
|---|---|---|---|---|---|
| Diphtheria antitoxin (equine) | Horse-derived anti-diphtheria serum | Historical | Antitoxin (passive) | Historical (1890s) | Therapeutically used from 1890s; not a vaccine |
| Diphtheria toxoid | Formaldehyde-inactivated diphtheria toxin | Various | Toxoid | Licensed (in combinations) | Used since 1920s; always in combination today |
| Decavac | Td (tetanus + diphtheria adult) | Sanofi Pasteur | Toxoid combination | FDA Licensed; Discontinued | Adult Td booster; discontinued |
Sources
Regulatory data sourced from FDA CBER Vaccines Licensed for Use in the United States (March 2026). Catalog scope and historical context informed by Khan, Shaz, The Ultimate Vaccine Timeline.