Tick-Borne Encephalitis Vaccines

Inactivated viral vaccines for TBE prevention in endemic regions

This page catalogs 3 tick-borne encephalitis vaccine products spanning the first US-licensed TBE vaccine and established European formulations. TBE vaccination has been routine in endemic European countries for decades, with the 2021 US licensure of Ticovac representing the first FDA-approved option for American travelers to endemic regions.

Last updated: April 2026.

Tick-Borne Encephalitis Vaccine Catalog

Trade NameGeneric DesignationManufacturerVaccine TypeRegulatory Status & YearKey Notes
TicovacTick-borne encephalitis vaccinePfizerInactivated viralFDA Licensed, 2021First US-licensed TBE vaccine
FSME-ImmunTBE vaccinePfizer (Baxter legacy)Inactivated viralEMA AuthorizedEuropean TBE; same product as Ticovac
EncepurTBE vaccineGSK (Novartis legacy)Inactivated viralEMA AuthorizedEuropean TBE vaccine

Sources

Regulatory data sourced from FDA CBER Vaccines Licensed for Use in the United States (March 2026) and EMA Medicines database. Catalog scope informed by Khan, Shaz, The Ultimate Vaccine Timeline.