Lyme Disease Vaccines

Recombinant OspA vaccine (withdrawn)

This page catalogs 1 Lyme disease vaccine product. LYMErix was the only Lyme disease vaccine ever licensed for human use. It was voluntarily withdrawn from the market in 2002 due to low demand, not a regulatory safety action.

Last updated: April 2026.

Lyme Disease Vaccine Catalog

Trade NameGeneric DesignationManufacturerVaccine TypeRegulatory Status & YearKey Notes
LYMErixLyme disease vaccine (OspA)GSK (SmithKline Beecham)Recombinant OspAFDA Licensed, 1998; Withdrawn 2002Voluntarily withdrawn due to low demand

Sources

Regulatory data sourced from FDA CBER Vaccines Licensed for Use in the United States (March 2026) and FDA historical archives. Catalog scope informed by Khan, Shaz, The Ultimate Vaccine Timeline.