HPV Vaccines

Recombinant virus-like particle vaccines

This page catalogs 4 human papillomavirus (HPV) vaccine products. All HPV vaccines use recombinant virus-like particle (VLP) technology — self-assembling protein structures that mimic the virus surface but contain no viral genetic material. HPV vaccination targets cancer-causing HPV types and is recommended as part of routine adolescent immunization in the United States and many countries worldwide.

Last updated: April 2026.

HPV Vaccine Catalog

Trade NameGeneric DesignationManufacturerVaccine TypeRegulatory Status & YearKey Notes
GardasilHPV quadrivalent (6, 11, 16, 18) vaccineMerckRecombinant VLPFDA Licensed, 2006First HPV vaccine; superseded by Gardasil 9
Gardasil 9HPV 9-valent vaccineMerckRecombinant VLPFDA Licensed, 2014Current standard; covers 9 HPV types
CervarixHPV bivalent (16, 18) vaccineGSKRecombinant VLP + AS04FDA Licensed, 2009GSK bivalent; less used in US after Gardasil 9
CervavacHPV quadrivalent vaccineSerum Institute of IndiaRecombinant VLPLicensed in India, 2022India-developed affordable HPV vaccine

Sources

Regulatory data sourced from FDA CBER Vaccines Licensed for Use in the United States (March 2026) and India DCGI records. Catalog scope informed by Khan, Shaz, The Ultimate Vaccine Timeline.