Experimental vaccine candidates that reached advanced clinical trials
This page catalogs 1 HIV vaccine candidate that reached Phase III clinical trials. Despite decades of research, no HIV vaccine has achieved regulatory approval. AIDSVAX, the first HIV vaccine to complete Phase III trials, failed to demonstrate protective efficacy in 2003. HIV vaccine development remains an active area of research with multiple candidates in earlier-stage clinical trials.
Last updated: April 2026.
| Trade Name | Generic Designation | Manufacturer | Vaccine Type | Regulatory Status & Year | Key Notes |
|---|---|---|---|---|---|
| AIDSVAX | HIV gp120 subunit vaccine | VaxGen | Recombinant protein subunit | Phase III failed, 2003 | Failed to demonstrate efficacy in Phase III trials |
Clinical trial data sourced from published peer-reviewed literature. Catalog scope informed by Khan, Shaz, The Ultimate Vaccine Timeline.